Analysis of Nanoparticle Chemoattractant Properties Using Label-Free, Real-Time Chemotaxis Assay

Analysis of Nanoparticle Chemoattractant Properties Using Label-Free, Real-Time Chemotaxis Assay

Standard Number ITA-8.2
Organization Nanotechnology Characterization Laboratory USA
Level National
Category Test Method | Characterization | Measurement
Status
  • MAY 2020 Published
ABSTRACT
This document provides a protocol for a real-time, quantitative assessment of the chemoattractant capacity of engineered nanomaterials. Leukocyte recruitment is a central component of the inflammatory process in both host defense against pathogens and a range of inflammatory disorders. Leukocytes respond to pro-inflammatory stimuli, including but not limited to cytokines, chemokines, and prostaglandins, by migrating from the bloodstream to the site of inflammation.