Research & Science NEWS

HDL Nanoparticles Prevent Cholesterol Movement at Membrane Receptor to Inhibit Entry of SARS-CoV-2 Pseudovirus in Cell Culture

2020-12-22

HDL Nanoparticles Prevent Cholesterol Movement at Membrane Receptor to Inhibit Entry of SARS-CoV-2 Pseudovirus in Cell Culture

As researchers and physicians strive to find effective and safe therapeutics to counter the coronavirus disease 2019 (COVID 19), an interesting new study published in the bioRxiv* preprint server suggests that preventing the movement of cholesterol through its high-affinity cell membrane receptor scavenger receptor type B-1 (SR-B1) may inhibit viral entry by up to 80%. This reveals a...