NCL Method ITA-4 Analysis of Nanoparticle Interaction with Plasma Proteins by 2D PAGE

Proteins bind the surfaces of nanoparticles, and biological materials in general, immediately upon introduction of the materials into a physiological environment. The further biological response of the body is influenced by the nanoparticle–protein complex. The nanoparticle's composition and surface chemistry dictate the extent and specificity of protein binding.