Chemotaxis Assay
| Standard Number | ITA-8 |
|---|---|
| Organization |
Nanotechnology Characterization Laboratory
|
| Level | National |
| Category | Specification |
| Status |
|
ABSTRACT
This document provides a protocol for rapid, quantitative measure of the chemoattractant capacity of a nanoparticulate material. Leukocyte recruitment is acentral component of the inflammatory process, both in physiological host defense and in a range of prevalent disorders with an inflammatory component. In response to a complex network of pro inflammatory signaling molecules (including cytokines, chemokines and prostaglandins), circulating leukocytes migrate from the bloodstream to the site of inflammation.