Chemotaxis Assay
Standard Number | ITA-8 |
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Organization |
Nanotechnology Characterization Laboratory
|
Level | National |
Category | Specification |
Status |
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ABSTRACT
This document provides a protocol for rapid, quantitative measure of the chemoattractant capacity of a nanoparticulate material. Leukocyte recruitment is acentral component of the inflammatory process, both in physiological host defense and in a range of prevalent disorders with an inflammatory component. In response to a complex network of pro inflammatory signaling molecules (including cytokines, chemokines and prostaglandins), circulating leukocytes migrate from the bloodstream to the site of inflammation.