Researchers propose new strategy to improve efficiency for nanotherapeutic delivery in tumors

A team led by Prof. Wang Yucai and Associate Prof. Jiang Wei from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed the mechanism of the tumor vascular basement membranes (BM) blocking nanoparticles (NPs) for the first time and developed an immunodriven strategy to increase the NP penetration through the BM barrier. Their work was published in Nature Nanotechnology.