Exploration of individual colorectal cancer cell responses to H₂O₂ eustress

In a recent study published in the journal Science Bulletin, researchers from the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University utilized hopping probe scanning ion conductance microscopy (HPICM) and highly sensitive platinum-functionalized nanoelectrodes to conduct an in-depth investigation of the dynamic response of individual living colorectal cancer Caco-2 cells to changes in intracellular and extracellular hydrogen peroxide (H2O2) gradients, specifically focusing on eustress, at the single-cell level and in real-time.