Nanoparticles restore neurons in Parkinson's with wireless brain stimulation

Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction. Its pathological hallmark is the abnormal aggregation of α-synuclein (α-syn) into insoluble fibrils and Lewy bodies, leading to the degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain.