Ion-pair stealth shield hides nanoparticles from the body's defenses

Japan's Innovation Center of NanoMedicine reports on a new stealth coating for tiny medicine-carrying particles that doesn't depend on PEG-style shields. By locking positive and negative charges together into a tight net, the coating prevents protein buildup and avoids pickup by immune cells, so the particles stay in the blood for more than 100 hours. Packed with the enzyme asparaginase, the particles act like small reactors that drain asparagine to starve difficult-to-treat cancers.