The theranostic complex with two toxic modules shows great toxicity for tumour cells

Emerging cancer nanotechnology enables target-delivery of substantial payloads of drugs to cancer sites with concomitant reduction of side-effects due to the lesser accumulation in the critical organs. This prompts loading of nanocarriers with therapeutic cargo and contrast agents, allowing combined cancer therapy and tumour visualization, respectively. Researchers from Lobachevsky University of Nizhny Novgorod, Russia, have implemented such combined therapy using conjugates of radionuclide yttrium-90-doped upconversion nanoparticles (UCNP) and targeted toxin.