DNA-based nanocomposite hydrogel as a potent injectable drug delivery platform
Date | 24th, Sep 2018 |
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Source | Nanowerk - Nanotechnology Websites |
DESCRIPTION
Investigating the potential of DNA to form self-assembled injectable hydrogels via physical crosslinking with silicate nanodisks, researchers have utilized DNA as a high molecular weight polymeric chain in order to form hydrogel networks for tissue regeneration and drug delivery applications. They have designed shear thinning hydrogels, which can be passed through a 22-gauge syringe by taking advantage of the native chemical structure of DNA and its specific base pairing interactions.