Combination pack battles cancer: Nanoparticles with multifunctional drug precursor for synergistic tumor therapy

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. Scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer. This dimer can be incorporated into polymeric nanotransporters at exceptionally high concentration. The components are activated when the dimer is split within the tumor. In addition, they enable use of two different imaging techniques.