Design principles for peroxidase-mimicking nanozymes

Nanozymes, enzyme-like catalytic nanomaterials, are considered to be the next generation of enzyme mimics because they not only overcome natural enzymes' intrinsic limitations, but also possess unique properties in comparison with conventional artificial enzymes. Until now, lots of nanomaterials have been explored to mimic various natural enzymes, such as peroxidase, oxidase, catalase, and hydrolase. Particularly, enormous efforts have been devoted to peroxidase-like nanozymes because of their applications in biomedical diagnosis, bioimaging, anti-biofouling coatings, etc.