A new strategy to trigger ferroptosis in target cancer cells using drug-metal coordination complexes

Date 29th, Apr 2020
Source EurekAlert - Scientific News Websites

DESCRIPTION

Doxorubicin and ferrous ions could form acid-dissociable coordination complexes, which were incorporated into functionally tailored amorphous calcium carbonate nanoparticles and may confer severe ferroptotic damage to target tumor cells, published on Science Advances.