Nanoparticle drug-delivery system developed to treat brain disorders

To facilitate successful delivery of therapeutic agents to the brain, a team of bioengineers and physicians created a nanoparticle platform, which can facilitate therapeutically effective delivery of encapsulated agents in mice with a physically breached or intact BBB. In a mouse model of traumatic brain injury (TBI), they observed that the delivery system showed three times more accumulation in brain than conventional methods of delivery.