Breaching the blood-brain barrier to deliver precious payloads: Researchers use ultrasound to develop delivery system for potent RNA drugs

RNA-based drugs may change the standard of care for many diseases, making personalized medicine a reality. So far these cost-effective, easy-to-manufacture drugs haven't been very useful in treating brain tumors and other brain disease. But a team has shown that a combination of ultrasound and RNA-loaded nanoparticles can temporarily open the protective blood-brain barrier, allowing the delivery of potent medicine to brain tumors.