Can the diffraction limit overcome in the linear imaging system?

Spatial-frequency-shift microscopy with evanescent wave illumination shows intriguing advantages, including a large field of view, high speed, and good modularity. However, a missing band in the spatial frequency domain hampers the spatial-frequency-shift superresolution microscopy from achieving resolution better than 3 folds of the Abbe diffraction limit. Recently researchers at Zhejiang University have proposed chip-compatible wide-field 3D nanoscopy through tunable spatial frequency shift effect, making the diffraction limit overcome in the linear optical imaging system.