Non-magnetic shell coating of magnetic nanoparticles as key factor for cytotoxicity

Russian scientists have found that coating magnetic nanoparticles with a non-magnetic silica shell coating significantly decreased the viability of cancer cells in a low frequency alternating magnetic field. The coating increases nanoparticles stability, preventing aggregation in endosomes and keeping them as effective magneto-mechanical actuators in a low-frequency alternating magnetic field. The study was published in Colloids and Surfaces B: Biointerfaces.