Colorectal Cancer Drug Delivery System Combines Nanoparticles and Hyaluronic Acid

A recent surge in using biomolecules as carrier systems led to the development of biomolecule-based nanoparticles (NPs) for cancer treatment. In an article recently published in the journal Materials Today Communications, authors developed encorafenib (ECF) encapsulated hyaluronic acid (HA)-decorated polycaprolactone (PCL) and polyhydroxybutyrate (PHB) polymeric NPs to treat colorectal cancer. They hypothesized that the synthesized NPs lowered reactive oxygen species (ROS) by cellular internalization and subsequent apoptotic arrest.