"Influence of nanoparticles, surrounding ions on formation of ?-sheet structure in amyloid ? proteins"

Date 14th, Jul 2022
Source Phys.org - Scientific News Websites

DESCRIPTION

Protein function and activity are determined by both their assembly and secondary structure. Abnormalities related to either protein aggregation or secondary structure can lead to neurodegenerative diseases. In a new study, an international research team reveals how fluoride nanoparticles, materials used in in vivo imaging, affect the assembly and structure of the amyloid β protein. Their results present a step towards better treatment and prevention of neurologic disorders like Alzheimer's disease.