Have Cell Membrane Coated Nanoparticles Been Wrongly Understood?

Date 21st, Sep 2022
Source AZoNano - Nanotechnology Websites

DESCRIPTION

Negative staining is often used to study the characteristic core-shell structure of cell membrane (CM)-coated polymeric nanoparticles (NPs) via transmission electron microscopy (TEM). However, negative staining can develop artifacts that pose difficulties for detecting the actual NP structure.