Embedding aligned nanofibrous architectures within 3D-printed polycaprolactone scaffolds for tissue regeneration

The existing 3D-printed scaffolds commonly possess a thick feature size of hundreds of micrometers, which is too large for most cells (10–20 μm) to attach and proliferate for promoting tissue regeneration. Researchers from Xi'an Jiaotong University have developed a novel hybrid manufacturing technique for the fabrication of composite scaffolds with 3D-printed macroscale frameworks and aligned nanofibrous architectures to improve cellular organizations.