The Nanotechnology Products Database (NPD) monitored 222 nanoclay-based products on the global market by August 2020. The products are from 125 companies headquartered in 25 countries. Nanoclays and organoclays used in the products are mainly based on montmorillonite nanoparticles, bentonite nanoparticles, and halloysite nanotubes. According to the NPD, the United States, China, Japan, India, the United Kingdom, Russia, and South Korea are currently the major manufacturers of nanoclay-based products. The integration of nanoclay into the design of these products enhances their different properties such as mechanical strength, thermal stability, anti-settling properties, ultraviolet scattering, permeability to gases, photostability, rheology modification, viscosity control, surface contaminant removal, hydrophobicity, oil resistance, chemical resistance in acidic or alkaline media, corrosion and oxidation resistance, anti-bacterial, anti-microbial, and antifungal properties, and biodegradability. Rheology modifiers, nanocomposites, water filtration media, car wash products, toothpaste and mouthwash, drilling mud, food packaging films, tires, greases, lubricants, polishes, tennis balls, cosmetic additives, paints, thermal insulation coatings, cables, inks, asphalt additives, screws, panels, board fences, glues, and syringes are among the products reviewed here.