Date13th, Feb 2024

Summary:

In a study published in Nature Nanotechnology, scientists from Delft University of Technology present a new technique to identify proteins. Proteins carry out essential functions in our cells, while playing a crucial role in diseases like cancer and COVID-19 infection. The researchers identify proteins by reading out the fingerprint, and comparing the fingerprint to patterns from a database. Using this new technology, the researchers can identify individual, intact, full-length proteins, preserving all its information. This can shed light on the mechanisms behind many different diseases and allows earlier diagnosis.

Full text:

The illustration shows a human protein and amino acid code in the background. The new FRET X technology is capable of identifying proteins using protein fingerprints. The Chirlmin Joo Lab obtains these unique fingerprints by finding part of the full-length amino acid code (the highlighted C’s and K’s among the blue letters).