Nanopore technology has emerged as a powerful tool for single-molecule sensing, offering unprecedented capabilities in fields ranging from DNA nanopore sequencing to protein analysis. These nanoscale pores, whether biological or solid-state, act as molecular gateways, allowing researchers to detect and analyze individual molecules as they pass through. The principle behind nanopore sensing is elegantly simple: as a molecule traverses the pore, it disrupts the ionic current flowing through it, creating a characteristic signal that can be used to identify and study the molecule.
