Dissecting the mechanism of protein unfolding by SDS

Date	17th, Apr 2020

Summary:

A new study by the Aksimentiev group at the University of Illinois has used molecular dynamics simulations to understand how sodium dodecyl sulfate, a commonly used detergent in labs, induces protein folding. Their results were published in the journal Nanoscale.

Full text:

video: The video animation illustrates a domain of titin spontaneously unfolding in the presence of the SDS (red and cyan dots). SDS molecules are only shown when directly bound to titin. view more

Credit: Courtesy the Aksimentiev group.

Researchers at the

Source:

EurekAlert