The 2022 finalists will feature technological innovations in and beyond the areas of quantum computing, semiconductors, additive manufacturing, medical imaging, and displays.
The challenge is supported by founding partner Jenoptik; lead sponsors MKS Instruments, Hamamatsu, and Thorlabs; and strategic partners Aspire360 and NextCorps’ Luminate.

The 2022 SPIE Startup Challenge finalists:
• Ascend Manufacturing, with a novel 3D-printing technology.
• LightCare, with a smart, effective, and safe medical optics technology for muscle-training physiology.
• Luminess, with Luminess Detectors, a versatile platform for safer, more sensitive, and more reliable x-ray medical imaging.
• Modendo Inc., with ultrathin endomicroscopes that provide high-resolution optical imaging and photo-stimulation for currently inaccessible brain regions.
• Nicslab, with XDAC, a multichannel power driver that controls the light in PICs.
• ORCA Computing, using room-temperature and photonic-quantum-computing systems to solve complex machine-learning workloads.
• Phaseform, with a new approach to adaptive optics.
• Quantopticon, with simulation software for quantum photonic hardware manufacturers who want to build optimized quantum photonic devices.
• Specto Photonics, with next-generation miniaturized spectrometers to measure fundamental mechanical properties for life sciences and sensing applications.
• VitreaLab, with a laser-lit chip for the 2D- and 3D-display market.
