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Every cell relies on the uptake (endocytosis) of materials like proteins, cytokines and even synthetic carbon nanomaterials, to perform its required cellular fate functions. Studying this process in detail is an extremely challenging and thus extremely interesting goal in biophysics. Therefore, endocytosis is of interest for bringing therapeutic targets into cells. Studying the pathways of how materials get into the cell can aid in untangling trafficking to design higher efficiency targeted drug and gene delivery therapies.