The incorporation of #polyethylene_glycol (PEG) chains into proteins, polypeptides, and aptamers enhances their #hydrodynamic radius while reducing their #proteolysis.
The first #FDA-approved #nanoliposomal drug is #liposomal #doxorubicin which employs 100-nm liposomes modified by #polyethylene_glycol (PEG) chains, using the PEGylation process.