Standard Test Method for Measuring the Size of Nanoparticles in Aqueous Media Using Dynamic Light Scattering

Standard Test Method for Measuring the Size of Nanoparticles in Aqueous Media Using Dynamic Light Scattering

Standard Number ASTM E3247 - 20
Organization American Society for Testing and Materials USA
Level National
Category Test Method | Characterization | Measurement
Status
  • SEP 2020 Published
ABSTRACT
This test method addresses the determination of nanoparticle size (equivalent sphere hydrodynamic diameter) using batch-mode (off-line) dynamic light scattering (DLS) in aqueous suspensions and establishes general procedures that are applicable to many commercial DLS instruments. This test method specifies best practices, including sample preparation, performance verification, data analysis and interpretation, and reporting of results. The document includes additional general information for the analyst, such as recommended settings for specific media, potential interferences, and method limitations. Issues specific to the use of DLS data for regulatory submissions are addressed.