Standard Test Method for Analysis of Hemolytic Properties of Nanoparticles

Standard Test Method for Analysis of Hemolytic Properties of Nanoparticles

Standard Number ASTM E2524 - 08(2013)
Organization American Society for Testing and Materials USA
Level National
Category Test Method | Characterization | Measurement
Status
  • JAN 2008 Published
  • JAN 2013 Reviewed and Confirmed
ABSTRACT
1.1This test method covers assessing the effect of nanoparticulate materials on the integrity of red blood cells. 1.2 This test method uses diluted whole blood incubated with nanoparticulate material and the hemoglobin released from damaged red blood cells is determined. 1.3 This test method is similar to Practice F756 with the volumes reduced to accommodate nanoparticulate material. 1.4 This test method is part of the in-vitro preclinical characterization and is important for nanoparticulate material that will contact the blood in medical applications.