NCL Method ITA-4 Analysis of Nanoparticle Interaction with Plasma Proteins by 2D PAGE

NCL Method ITA-4 Analysis of Nanoparticle Interaction with Plasma Proteins by 2D PAGE

Standard Number ITA-4
Organization Nanotechnology Characterization Laboratory USA
Level National
Category Specification
Status
  • JAN 2010 Published
ABSTRACT
Proteins bind the surfaces of nanoparticles, and biological materials in general, immediately upon introduction of the materials into a physiological environment. The further biological response of the body is influenced by the nanoparticle–protein complex. The nanoparticle's composition and surface chemistry dictate the extent and specificity of protein binding.