Analysis of Platelet Aggregation by Cell Counting

Analysis of Platelet Aggregation by Cell Counting

Standard Number ITA-2.1
Organization Nanotechnology Characterization Laboratory USA
Level National
Category Test Method | Characterization | Measurement
Status
  • MAY 2020 Published
ABSTRACT
This document describes a procedure for analysis of platelet aggregation. Platelets are small (~2μm) anuclear cells obtained by fragmentation of megakaryocytes. Platelets, also known as thrombocytes, play a key role in hemostasis. Abnormal platelet counts and function may lead to either bleeding or thrombosis. Assessing nanoparticle effects on human platelets in vitro allows for quick screening of their potential anticoagulant or thrombogenic properties mediated by direct effects on platelets.