Highlights

Latest Nanotechnology vs. Coronavirus Highlights

▌Specific benefits of Outer Membrane Vesicles (OMV) based #COVID_19 #vaccine include easier and non-invasive administration, rapid cost-effective production, potent intrinsic adjuvanticity and the increased safety and stability of OMV. | more

▌PAC-MAN technology is composed of the virus-killing #enzyme Cas13 and a strand of guide RNA, which commands Cas13 to destroy specific nucleotide sequences in the #SARS_CoV_2 genome. | more

▌Multi-drug nanoparticles containing #adenosine and #squalene, encapsulated in a type of #vitamin_E can help humans fight off the severe #cytokine_storm that occurs in severe cases of #COVID_19. | more

▌The #STARR technology platform combines self-replicating #RNA with LUNAR, a leading nanoparticle non-viral delivery system, to produce proteins inside the human body. | more

▌Three #vaccine candidates based on the #horsepox vector platform designed to express various SARS-CoV-2 antigens. | more

▌Production of the #virus_like_particle (VLP) is the first step in developing a #vaccine for #COVID_19, which will now undergo preclinical testing for safety and efficacy by Medicago. | more

▌A #DNA-based #vaccine candidate for #COVID_19 worked by using engineered bacteriophage can be delivered through a #nasal_spray. | more

▌Face #masks combined with one layer of a tightly woven #cotton sheet and two layers of polyester-spandex chiffon can effectively filter out #aerosol particles ranging from 10 nm to 6 μm in diameter. | more

▌A mineral #nanocrystal based coating when is charged by any visible light and creates a potent oxidation reaction that completely breaks down any organic contaminants including #viruses and bacterias. | more

▌Iran, a country under a series of bitter US sanctions, is launching the largest #N95_mask plant in West Asia with a production capacity of 4 million per day, relying on electrospun #nanofiber technology. | more

▌Oxford #nanopore MinION device is the only portable and real-time device that allows for DNA and RNA #sequencing analysis of the samples collected from all patients with positive #COVID_19 tests. | more

▌The 2nd generation development of the #COVID_19 rapid antibody IgM/IgG test has seen the introduction of #gold_nanoparticles into the testing strip. | more

#Silica-coated #iron_oxide nanoparticles have a strong affinity for #RNA that can be used to extract #coronavirus RNA from a solution containing a sample from the patient.| more

▌In PreLynx #sanitizer a #nanopolymer disinfectant vapor containing a potent #virucidal agent inactivates all of the lipophilic viruses including herpes, influenza, and #coronavirus within twenty minutes. | more

▌Janssen #AdVac technology is a technology based on the #adenovirus vector that can be used together with PER.C6 technology to develop recombinant #vaccines against life-threatening infectious diseases. | more

▌Laser-induced #graphene that can conduct electrical charge to kill the trapped #microorganisms in the mask filter, is effective in blocking out 99 percent of particles over 0.3 micrometers and 80 percent of smaller particles. | more

#Nanomedicine research about the role of #chloroquine in #nanoparticle uptake in cells showed promise in developing an effective treatment for #COVID_19. | more

#Nanofiber face masks and #respirators enriched with accelerated #copper_oxide not only mechanically intercept #viruses and bacteria, they actively kill them as well. | more

▌A consortium of international partners are working to develop a functional prototype for an antigen detecting, rapid-response,
#lateral_flow test for #COVID_19. | more

▌Tailored surfaces formed of a mixture of #polyethylene and #graphite_nanoplatelets can kill 99.99 percent of #bacteria which try to attach to the surface. | more

▌The #nanomaterials with enzyme-like characteristics developed by Chinese researchers can absorb and deactivate the #coronavirus (SARS-CoV-2) with 96.5 - 99.9 percent efficiency. | more

▌The rapid #COVID_19 test based on IgG-IgM combined #antibody and #gold_nanoparticles has great potential benefit for the fast screening of COVID-19 infections within 15 minutes. | more

▌Recent Alnylam advances in lung delivery technology suggest the possible utility of #RNAi therapeutic for the treatment of new #coronavirus disease (COVID-19). | more

▌SNALP is a #lipid_nanoparticle based #siRNA trigger formulation that comprises ionizable lipids, shielding lipids, cholesterol, and endogenous or exogenous targeting ligands such as ApoE lipoprotein. | more

#Ad5_nCoV is a genetically engineered #vaccine candidate with the replication-defective #adenovirus type 5 as a vector to express the spike protein of the novel #coronavirus (SARS-CoV-2). | more

▌A particular antibacterial substance composed of #titanium_dioxide and #silver nanoparticles makes the surfaces #self_sterilizing from six months to two years. | more

▌Using an insulation block #electrospinning process to manufacture orthogonal #nanofibers by controlling the alignment of nanofibers Korean researchers succeeded in developing a washable nanofiber-based face mask. | more

▌The colorimetric based #MIT technology can detect the #SARS_CoV_2 within 20 minutes using nanoparticle-bound #antibodies against a specific viral protein. | more

▌The first step in the clinical development of #Moderna's #mRNA vaccine against #SARS_CoV_2 (mRNA-1273) is being conducted by #NIH under its own Investigational New Drug application. | more

#mRNA technology has been widely used in many #nanotechnology_patents focusing on the #coronavirus (SARS / MERS) treatment approaches. | more

▌A vast majority of #nanotechnology_patents on #coronaviruses have focused on the #diagnostic methods based on #CRISPR technology. | more

▌The future of #therapeutics is potent biological drugs, many of which have #delivery challenges with respect to how much drug needs to be delivered to exactly where in the body, while minimizing #side_effects. | more

▌Around 5.2 percent (478 patents) of all #coronavirus related patents so far registered are in the field of #nanotechnology. | more

▌Tulane National Primate Research Center (TNPRC) is establishing a #COVID_19 research program to develop a #vaccine and test treatments against the virus. | more

▌Loading #antiviral agents on #graphene_oxide (GO) enhances its biocompatibility while reducing the cytotoxicity of both GO and the antiviral agents. | more

▌New #COVID_19 vaccine candidate has been developed using proprietary #recombinant_protein nanoparticle technology platform to generate antigens derived from the #coronavirus spike (S) protein. | more

▌Integrating a proprietary #nanorod technology into a #lateral_flow_test platform resulted in developing of a rapid screening test for the current #coronavirus, nCoV19. | more

▌Carbon #quantum_dots functionalized with boronic acid ligands can interfere with the function of #coronavirus S protein and significantly inhibit its entry into the host cells. | more

#Nanofiber based #N95_respirators can block out at least 95 percent of the airborne particles larger than 2.5 microns, including droplets carrying #viruses and #bacteria. | more

▌Due to their two-dimensional structure, sharp edges, and negatively charged surfaces, #graphene_oxide nanosheets are capable of interacting with microorganisms such as #bacteria and #viruses. | more

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